Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249973 | 0.69 | KMT2A (0.42) | CA1CA2MEN1KMT2ARAB9A | |
| SCHEMBL5308983 | 0.69 | CA1 (0.51) | LMNACA1CA2L3MBTL1MEN1 | |
| Benzaldehyde Oxime SCHEMBL6416027 | 0.69 | KMT2A (0.53) | LMNACA1CA2L3MBTL1MEN1 | |
| SCHEMBL6249968 | 0.69 | KMT2A (0.42) | CA1CA2MEN1KMT2ARAB9A | |
| SCHEMBL5308988 | 0.69 | CA1 (0.51) | LMNACA1CA2L3MBTL1MEN1 | |
| SCHEMBL11167912 | 0.68 | CA1 (0.46) | LMNACA1CA2L3MBTL1MEN1 | |
| SCHEMBL11167907 | 0.68 | CA1 (0.46) | LMNACA1CA2L3MBTL1MEN1 | |
| SCHEMBL6416021 | 0.67 | PLA2G7 (0.61) | CA1CA2MEN1KMT2ARAB9A | |
| SCHEMBL15672276 | 0.67 | LMNA (0.82) | LMNAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL4338307 | 0.67 | ALDH1A1 (0.40) | LMNACA1CA2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |