Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218065 | 0.83 | POLB (0.35) | ADRB2ADRB1ADRB3POLBMAPT | |
| SCHEMBL7469139 | 0.82 | PTPN11 (0.39) | ADRB2ADRB1ADRB3POLBPTPN11 | |
| SCHEMBL9220084 | 0.82 | POLB (0.34) | ADRB2ADRB1ADRB3POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL8742747 | 0.79 | PTPN11 (0.37) | ADRB2ADRB1ADRB3PTPN11 | |
| SCHEMBL9221585 | 0.79 | GPR119 (0.47) | TSHR | |
| Water SCHEMBL8742754 | 0.74 | PTPN11 (0.36) | MAPTPTPN11USP2ALDH1A1TSHR | |
| SCHEMBL9219229 | 0.72 | NPSR1 (0.43) | MAPT | |
| SCHEMBL7470458 | 0.71 | PTPN11 (0.40) | POLBMAPTPTPN11LMNATHRB | |
| SCHEMBL9215473 | 0.69 | NPSR1 (0.38) | MAPTLMNAALDH1A1 | |
| SCHEMBL9218048 | 0.69 | ABCC9 (0.39) | MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |