Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 6/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220084 | 0.94 | POLB (0.34) | POLBKDM1AKDM1BMAOBTP53 | |
| SCHEMBL9221585 | 0.84 | GPR119 (0.47) | TSHR | |
| SCHEMBL7466247 | 0.83 | PTPN11 (0.39) | POLBKDM1AKDM1BMAOBTP53 | |
| SCHEMBL9212836 | 0.83 | ADRB2 (0.37) | POLBTP53PTPN11LMNAADRB2 | |
| SCHEMBL9212184 | 0.83 | NPSR1 (0.35) | TP53MAPT | |
| SCHEMBL7466955 | 0.77 | PTPN11 (0.37) | POLBTP53PTPN11LMNAMAPT | |
| SCHEMBL9211583 | 0.76 | NPSR1 (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL8742909 | 0.74 | PTPN11 (0.35) | POLBKDM1AKDM1BTP53PTPN11 | |
| SCHEMBL9218026 | 0.74 | NPSR1 (0.39) | MAPT | |
| SCHEMBL7471039 | 0.69 | NPSR1 (0.37) | TP53LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |