Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568423 | 0.94 | TGFBR1 (0.49) | TGFBR1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL21568424 | 0.90 | TGFBR1 (0.46) | TGFBR1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL391000 | 0.87 | CYP1A2 (0.59) | TGFBR1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL9217259 | 0.86 | TLR8 (0.52) | TGFBR1ALDH1A1TLR8TP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9472571 | 0.85 | TLR8 (0.51) | TGFBR1ALDH1A1TLR8TP53L3MBTL1 | |
| SCHEMBL21568422 | 0.84 | TGFBR1 (0.41) | TGFBR1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL15470590 | 0.77 | CCR1 (0.65) | TGFBR1CCR1CCR8KDM4EIDH1 | |
| SCHEMBL23182746 | 0.76 | NPSR1 (0.51) | ALDH1A1MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL13309757 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL12963699 | 0.72 | NOS3 (0.55) | ALDH1A1TLR8LMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407899-B1 | Aminopyrimidine derivatives, process for their preparation, agent containing them and their use as fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-01 | — | — | EP | disclosed |
| EP-0407899-A2 | Aminopyrimidine derivatives, process for their preparation, agent containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1991-01-16 | — | — | EP | disclosed |