SCHEMBL921310

SCHEMBL921310

Cc1ccc(C(=O)NCc2ccc(Oc3ccccc3OC(F)(F)F)cc2)c(N)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KLKB1 P03952 1/20 0.45
MAPK14 Q16539 4/20 0.44
PDE2A O00408 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43
ADORA1 P30542 1/20 0.43
CARM1 Q86X55 2/20 0.43
PRMT6 Q96LA8 2/20 0.43
EPHX2 P34913 1/20 0.43
NR1H4 Q96RI1 1/20 0.43
HTR2C P28335 1/20 0.42
EGFR P00533 1/20 0.42
BTK Q06187 1/20 0.42
PPARG P37231 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919533 0.92 ADORA2A (0.42) ALDH1A1GAAHPGDHTTATM
SCHEMBL920363 0.90 EPHX2 (0.51) KLKB1MAPK14PDE2AADORA2AADORA1
SCHEMBL920866 0.89 MAPK14 (0.44) ALDH1A1GAAHPGDHTTATM
SCHEMBL921586 0.89 L3MBTL1 (0.46) ALDH1A1GAAHPGDHTTATM
SCHEMBL920313 0.89 CARM1 (0.55) ALDH1A1GAAHPGDHTTATM
SCHEMBL922269 0.88 HTT (0.47) ALDH1A1GAAHPGDHTTATM
SCHEMBL921442 0.88 MAPK14 (0.58) ALDH1A1GAAHPGDHTTATM
SCHEMBL922738 0.87 PPARD (0.46) PDE2AEPHX2NR1H4HTR2CPPARG
SCHEMBL921942 0.87 HPGD (0.46) ALDH1A1GAAHPGDHTTATM
SCHEMBL920870 0.87 CARM1 (0.42) ALDH1A1GAAHPGDHTTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ALDH1A1 2743/4885GAA 3332/4885HPGD 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.