SCHEMBL920363

SCHEMBL920363

Cc1ccc(C(=O)NCc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)c(N)n1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 5/20 0.51
NR1H4 Q96RI1 1/20 0.51
PDE2A O00408 1/20 0.51
PPARA Q07869 6/20 0.49
PPARD Q03181 3/20 0.49
ADRB2 P07550 1/20 0.48
HTR2C P28335 1/20 0.47
KLKB1 P03952 1/20 0.47
PPARG P37231 3/20 0.46
MAPK14 Q16539 2/20 0.45
LIPG Q9Y5X9 1/20 0.44
ADORA2A P29274 2/20 0.44
ADORA1 P30542 1/20 0.44
EGLN1 Q9GZT9 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921462 0.92 PPARD (0.53) EPHX2NR1H4PDE2APPARAPPARD
SCHEMBL920558 0.91 LIPG (0.44) EPHX2NR1H4PDE2APPARAPPARD
SCHEMBL921051 0.90 MAPK14 (0.58) PPARAPPARDHTR2CPPARGMAPK14
SCHEMBL921310 0.90 ALDH1A1 (0.45) EPHX2NR1H4PDE2APPARAPPARD
SCHEMBL921034 0.89 MAPK14 (0.57) EPHX2PPARAPPARDPPARGMAPK14
SCHEMBL922738 0.89 PPARD (0.46) EPHX2NR1H4PDE2APPARAPPARD
SCHEMBL921155 0.89 ADORA2A (0.47) MAPK14LIPGADORA2AADORA1EGLN1
SCHEMBL919993 0.88 PPARD (0.45) EPHX2NR1H4PDE2APPARAPPARD
SCHEMBL921391 0.88 PPARA (0.43) EPHX2NR1H4PDE2APPARAPPARD
SCHEMBL922052 0.88 PPARD (0.43) EPHX2NR1H4PDE2APPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 EPHX2 3522/4885NR1H4 3344/4885PDE2A 3565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.