Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210057 | 0.85 | CA12 (0.39) | KMT2ATP53 | |
| SCHEMBL9206290 | 0.84 | HRH3 (0.33) | KMT2ASLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL9208097 | 0.84 | MCHR1 (0.40) | — | |
| SCHEMBL8566875 | 0.83 | BACE1 (0.40) | SLC6A2SLC6A4SLC6A3MAOBMAOA | |
| SCHEMBL9205120 | 0.83 | BACE1 (0.40) | SLC6A2SLC6A4SLC6A3MAOBMAOA | |
| SCHEMBL9213510 | 0.83 | MIF (0.31) | MAOBTP53 | |
| SCHEMBL9208921 | 0.82 | HTR1A (0.42) | KMT2AGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9204689 | 0.80 | ALOX5 (0.44) | KMT2AMAOBMAOAKCNH2 | |
| SCHEMBL9215789 | 0.80 | ALOX5 (0.44) | KMT2AMAOBMAOAKCNH2 | |
| SCHEMBL9209400 | 0.80 | ALOX5 (0.44) | KMT2AMAOBMAOAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |