Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.31 |
| ▸ | REN | P00797 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205120 | 0.84 | BACE1 (0.40) | MAOBBRD4 | |
| SCHEMBL8566875 | 0.84 | BACE1 (0.40) | MAOBBRD4 | |
| SCHEMBL9210057 | 0.84 | CA12 (0.39) | TP53 | |
| SCHEMBL9206290 | 0.84 | HRH3 (0.33) | MAOBTP53HRH3 | |
| SCHEMBL9208097 | 0.84 | MCHR1 (0.40) | HRH3 | |
| SCHEMBL9213176 | 0.83 | PLA2G7 (0.35) | MAOBTP53 | |
| SCHEMBL9208921 | 0.81 | HTR1A (0.42) | TP53 | |
| SCHEMBL9213506 | 0.80 | MAOB (0.47) | MAOB | |
| SCHEMBL9204689 | 0.80 | ALOX5 (0.44) | MAOB | |
| SCHEMBL9215789 | 0.80 | ALOX5 (0.44) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| EP-0425209-A2 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |