Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92124 | 0.87 | CHRNB2 (0.45) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25665600 | 0.82 | EPHX1 (0.44) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12523122 | 0.80 | MAPK1 (0.44) | TSHRMAPK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL85847 | 0.80 | ACHE (0.36) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12385783 | 0.78 | ALDH1A1 (0.43) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19343428 | 0.78 | ACHE (0.40) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13336620 | 0.77 | ACHE (0.49) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20800956 | 0.76 | MEN1 (0.51) | MEN1KMT2A | |
| SCHEMBL85848 | 0.76 | CYP2D6 (0.43) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14493157 | 0.76 | KMT2A (0.48) | TSHRMAPK1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8128393-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |