Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92136 | 0.80 | ACHE (0.40) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL85834 | 0.78 | THRB (0.40) | ACHELMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL92124 | 0.78 | CHRNB2 (0.45) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25665600 | 0.77 | EPHX1 (0.44) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19356088 | 0.75 | CHRNB2 (0.41) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20800956 | 0.75 | MEN1 (0.51) | MEN1KMT2A | |
| SCHEMBL23056273 | 0.74 | ACHE (0.45) | ACHELMNAMEN1KMT2A | |
| SCHEMBL12385783 | 0.73 | ALDH1A1 (0.43) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13336620 | 0.72 | ACHE (0.49) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL24451569 | 0.72 | THRB (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8128393-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20080131692-A1 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. | 2008-06-05 | — | — | US | disclosed |