SCHEMBL921368

SCHEMBL921368

COc1ccc(COc2cccc(CNC(=O)c3cccnc3N)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.60
KMT2A Q03164 3/20 0.60
ALDH1A1 P00352 2/20 0.58
KDM4E B2RXH2 1/20 0.58
USP2 O75604 1/20 0.58
LMNA P02545 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MEN1 O00255 2/20 0.53
MAPT P10636 2/20 0.53
POLB P06746 2/20 0.52
APEX1 P27695 1/20 0.52
MMP13 P45452 1/20 0.52
SMPD1 P17405 1/20 0.51
RAB9A P51151 2/20 0.51
EGLN1 Q9GZT9 1/20 0.51
ROCK1 Q13464 2/20 0.50
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921909 0.94 KMT2A (0.66) HPGDKMT2AALDH1A1KDM4EUSP2
SCHEMBL923305 0.92 HPGD (0.60) HPGDKMT2AALDH1A1KDM4EUSP2
SCHEMBL919787 0.91 MAPK8 (0.56) HPGDKMT2AALDH1A1KDM4EUSP2
SCHEMBL921980 0.91 HPGD (0.64) HPGDKMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL923068 0.90 HPGD (0.72) HPGDKMT2AALDH1A1KDM4EUSP2
SCHEMBL920077 0.90 HPGD (0.62) HPGDKMT2AALDH1A1KDM4EUSP2
SCHEMBL921514 0.89 LMNA (0.55) HPGDKMT2AALDH1A1KDM4EUSP2
SCHEMBL921981 0.87 HPGD (0.70) HPGDKMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL922644 0.87 HPGD (0.57) HPGDKMT2AALDH1A1KDM4EUSP2
SCHEMBL920983 0.86 HPGD (0.67) HPGDKMT2AALDH1A1KDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885KMT2A 2469/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.