SCHEMBL921980

SCHEMBL921980

COc1ccc(COc2ccc(CNC(=O)c3cccnc3N)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
LMNA P02545 2/20 0.64
EGLN1 Q9GZT9 1/20 0.58
KMT2A Q03164 4/20 0.57
MAPT P10636 3/20 0.57
MEN1 O00255 3/20 0.57
ALDH1A1 P00352 3/20 0.56
RAB9A P51151 2/20 0.55
NPC1 O15118 1/20 0.55
POLB P06746 2/20 0.54
HTT P42858 1/20 0.52
HDAC1 Q13547 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921981 0.94 HPGD (0.70) HPGDSMN1; SMN2LMNAEGLN1KMT2A
SCHEMBL922511 0.91 HPGD (0.60) HPGDSMN1; SMN2LMNAEGLN1MAPT
SCHEMBL922540 0.91 MAPK8 (0.58) HPGDSMN1; SMN2LMNAKMT2AMAPT
SCHEMBL13070250 0.91 HPGD (0.66) HPGDSMN1; SMN2LMNAEGLN1KMT2A
SCHEMBL921037 0.91 HPGD (0.66) HPGDSMN1; SMN2LMNAEGLN1KMT2A
SCHEMBL923305 0.91 HPGD (0.60) HPGDSMN1; SMN2LMNAEGLN1KMT2A
SCHEMBL921368 0.91 HPGD (0.60) HPGDSMN1; SMN2LMNAEGLN1KMT2A
SCHEMBL922058 0.90 MAPK8 (0.59) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL12352271 0.89 KMT2A (0.59) HPGDSMN1; SMN2LMNAKMT2AMAPT
SCHEMBL1681107 0.89 KMT2A (0.59) HPGDSMN1; SMN2LMNAKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885SMN1; SMN2 4796/4885LMNA 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.