Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.32 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.32 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219764 | 0.85 | AR (0.36) | SIRT2SNCAIP6K1ARANO1 | |
| SCHEMBL9212713 | 0.84 | SIRT2 (0.35) | SIRT2SNCAIP6K1ARANO1 | |
| SCHEMBL9212102 | 0.77 | ROCK2 (0.36) | IP6K1ANO1 | |
| SCHEMBL9212183 | 0.76 | BRD4 (0.33) | IP6K1ANO1 | |
| SCHEMBL7466211 | 0.75 | HDAC1 (0.45) | HDAC1HDAC6 | |
| SCHEMBL9217957 | 0.73 | MAPK8 (0.37) | CBX7CDYL2CDYLCDY1; CDY1BGRIN1 | |
| SCHEMBL8593769 | 0.70 | MEN1 (0.34) | ANO1GRIN1GRIN2AMAPK1 | |
| SCHEMBL9220670 | 0.68 | ROCK2 (0.36) | SIRT2IP6K1IMPDH2LMNA | |
| SCHEMBL7470112 | 0.68 | HDAC1 (0.43) | DGAT2HDAC1HDAC6 | |
| SCHEMBL7477811 | 0.68 | HDAC1 (0.43) | DGAT2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |