Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 7/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218597 | 0.87 | HPGD (0.37) | ROCK2ROCK1HPGDCPT1AIP6K1 | |
| SCHEMBL9218306 | 0.86 | ACLY (0.33) | ROCK2ROCK1CPT1AACLY | |
| SCHEMBL9212844 | 0.82 | THRB (0.33) | ROCK2ROCK1CPT1APDE4DLMNA | |
| SCHEMBL9222097 | 0.80 | NPSR1 (0.34) | LMNATSHRACLY | |
| SCHEMBL9219603 | 0.79 | ACLY (0.33) | ROCK2ROCK1CPT1AACLY | |
| SCHEMBL9212102 | 0.79 | ROCK2 (0.36) | ROCK2ROCK1HPGDIP6K1PDE4D | |
| SCHEMBL9220003 | 0.78 | ANO1 (0.37) | ROCK2ROCK1IP6K1PDE4DHDAC8 | |
| SCHEMBL7472589 | 0.78 | AVPR1B (0.44) | — | |
| SCHEMBL9221306 | 0.77 | IDH1 (0.34) | CPT1AACLY | |
| SCHEMBL9211589 | 0.76 | MAPT (0.37) | HPGDLMNAACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |