Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212102 | 0.86 | ROCK2 (0.36) | ROCK2ROCK1ANO1HDAC8IP6K1 | |
| SCHEMBL9220003 | 0.84 | ANO1 (0.37) | ROCK2ROCK1ANO1HDAC8IP6K1 | |
| SCHEMBL7462162 | 0.80 | MAPT (0.39) | DRD2DRD4DRD3MDM4MDM2 | |
| SCHEMBL9213702 | 0.76 | SIRT2 (0.34) | ANO1IP6K1 | |
| SCHEMBL9220670 | 0.72 | ROCK2 (0.36) | ROCK2ROCK1HDAC8IP6K1PDE4D | |
| SCHEMBL7468992 | 0.71 | MAPT (0.37) | BRD4HDAC8DRD2DRD4DRD3 | |
| SCHEMBL9218597 | 0.70 | HPGD (0.37) | ROCK2ROCK1HDAC8IP6K1MDM2 | |
| SCHEMBL9219764 | 0.70 | AR (0.36) | ANO1IP6K1 | |
| SCHEMBL7471675 | 0.69 | OXTR (0.43) | PTGDR2 | |
| SCHEMBL9212844 | 0.68 | THRB (0.33) | ROCK2ROCK1HDAC8PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |