Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217003 | 0.91 | LOX (0.50) | LOXDHFRTSHRSMN1; SMN2TDP1 | |
| SCHEMBL19407960 | 0.84 | KMT2A (0.61) | LOXTDP1GAACYP2C19CA12 | |
| SCHEMBL4655576 | 0.82 | L3MBTL1 (0.70) | LOXL3MBTL1KMT2AMAPT | |
| SCHEMBL9222044 | 0.81 | ALDH1A1 (0.69) | LOXPKMCYP2C19CA12CA1 | |
| SCHEMBL22015808 | 0.81 | CA2 (0.54) | DHFRTSHRSMN1; SMN2TDP1GAA | |
| SCHEMBL917443 | 0.80 | GAA (0.57) | DHFRTSHRSMN1; SMN2TDP1GAA | |
| SCHEMBL3182581 | 0.80 | GAA (0.55) | LOXDHFRTSHRSMN1; SMN2TDP1 | |
| SCHEMBL8617225 | 0.79 | LOX (0.50) | LOXGAAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9316766 | 0.79 | ALDH1A1 (0.67) | DHFRTSHRSMN1; SMN2TDP1GAA | |
| SCHEMBL10688276 | 0.76 | GAA (0.52) | DHFRTSHRSMN1; SMN2TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002848-A1 | MULTIFUNCTIONAL AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |