Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874006 | 0.83 | HTT (0.62) | ALDH1A1KMT2AHTTGAALMNA | |
| SCHEMBL6911921 | 0.83 | ALDH1A1 (0.69) | ALDH1A1KMT2AHTTGAALMNA | |
| SCHEMBL6915414 | 0.81 | ALDH1A1 (0.66) | ALDH1A1KMT2AHTTGAALMNA | |
| SCHEMBL28897130 | 0.81 | KMT2A (0.53) | ALDH1A1KMT2AHTTGAALMNA | |
| Ethylene SCHEMBL9048687 | 0.80 | KMT2A (0.65) | ALDH1A1KMT2AHTTGAALMNA | |
| SCHEMBL9214290 | 0.79 | LOX (0.57) | ALDH1A1KMT2AGAALMNAPOLB | |
| SCHEMBL10752864 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KMT2AHTTGAALMNA | |
| SCHEMBL7867055 | 0.78 | LMNA (0.55) | ALDH1A1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL5711929 | 0.77 | CA2 (0.54) | ALDH1A1KMT2AHTTGAALMNA | |
| SCHEMBL4617628 | 0.77 | KMT2A (0.74) | ALDH1A1KMT2ALMNATSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510480-B1 | Process for the continuous preparation of aminoaryl or aminoalkyl beta-sulfatoethyl sulfones | HOECHST AG (DE) | 1994-12-14 | — | — | EP | disclosed |
| CN-1066061-A | The ammonia aryl-or aminoalkyl β-sulfato ethyl continuous preparation method of sucking sulfone | HOECHST AG (DE) | 1992-11-11 | — | — | CN | disclosed |
| EP-0510480-A1 | Process for the continuous preparation of aminoaryl or aminoalkyl beta-sulfatoethyl sulfones | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |