Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214012 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9211090 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9221753 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9209696 | 0.73 | HTR2A (0.47) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9211866 | 0.71 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| Fumaric Acid SCHEMBL9209066 | 0.71 | HTR2A (0.41) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9213959 | 0.71 | EPHA2 (0.48) | KDM4EALDH1A1KMT2AHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9217598 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL29483703 | 0.69 | IRAK4 (0.41) | SMN1; SMN2 | |
| SCHEMBL30589849 | 0.68 | HRH3 (0.62) | KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |