SCHEMBL921446

SCHEMBL921446

N#Cc1ccccc1COc1ccc[c]c1F

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.48
KMT2A Q03164 1/20 0.45
SGMS2 Q8NHU3 2/20 0.41
MCL1 Q07820 1/20 0.40
FFAR1 O14842 1/20 0.40
ALDH1A1 P00352 5/20 0.40
MAPK14 Q16539 1/20 0.40
TSHR P16473 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.37
MAOB P27338 1/20 0.37
PKM P14618 1/20 0.37
KDM4E B2RXH2 2/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920526 0.80 MCL1 (0.56) KMT2AMCL1ALDH1A1MAOBPKM
SCHEMBL921903 0.78 CDK4 (0.48) SGMS2MCL1ALDH1A1TSHRMAOB
SCHEMBL920301 0.78 HPGD (0.48) MCL1ALDH1A1TSHRMAOBKDM4E
SCHEMBL919555 0.78 IDO1 (0.51) SGMS2MCL1ALDH1A1PKM
SCHEMBL920567 0.77 GAA (0.46) ALDH1A1MAPK14TSHRKDM4E
SCHEMBL11425815 0.76 FFAR1 (0.44) PLAUKMT2ASGMS2FFAR1ALDH1A1
SCHEMBL920831 0.75 MAOB (0.47) FFAR1ALDH1A1MAPK14TSHRMAOB
SCHEMBL30331042 0.74 MCL1 (0.56) PLAUKMT2AMCL1ALDH1A1MAPK14
SCHEMBL29787368 0.74 PLAU (0.53) PLAUKMT2ASGMS2FFAR1ALDH1A1
SCHEMBL8395008 0.74 PLAU (0.53) PLAUKMT2ASGMS2FFAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PLAU 4417/4885KMT2A 2469/4885SGMS2 3358/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 PLAU 4833/4885KMT2A 1924/4885SGMS2 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.