SCHEMBL920567

SCHEMBL920567

N#Cc1ccccc1Oc1ccc[c]c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
POLB P06746 1/20 0.46
SLC22A12 Q96S37 1/20 0.38
FFAR4 Q5NUL3 1/20 0.36
MAP4K4 O95819 1/20 0.35
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
MAPK14 Q16539 1/20 0.35
GCK P35557 1/20 0.34
EZH2 Q15910 1/20 0.34
AR P10275 1/20 0.34
PIN1 Q13526 1/20 0.34
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TSHR P16473 1/20 0.33
LRRK2 Q5S007 1/20 0.33
ESRRA P11474 1/20 0.33
LPAR1 Q92633 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7054403 0.80 GAA (0.64) GAAPOLBSLC22A12MAP4K4PDE4A
SCHEMBL349000 0.78
SCHEMBL8431375 0.78 GAA (0.62) GAAPOLBSLC22A12MAP4K4PDE4A
SCHEMBL921446 0.77 PLAU (0.48) MAPK14ALDH1A1TSHRKDM4E
SCHEMBL30872202 0.77 POLB (0.53) GAAPOLBSLC22A12FFAR4MAP4K4
SCHEMBL18603934 0.77 POLB (0.53) GAAPOLBSLC22A12FFAR4MAP4K4
SCHEMBL920698 0.77 HTR1A (0.44) ALDH1A1KDM4E
SCHEMBL4831482 0.76 GAA (0.49) GAAPOLBMAP4K4PDE4APDE4B
SCHEMBL919267 0.75 SLC6A4 (0.46) GAAPOLBSLC22A12PDE4APDE4B
SCHEMBL920292 0.74 L3MBTL1 (0.48) GAAARALDH1A1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 GAA 3332/4885POLB 4159/4885SLC22A12 2533/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 GAA 2649/4885POLB 2580/4885SLC22A12 1551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.