Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209224 | 1.00 | TSHR (0.55) | TSHRRECQLSLC2A1RIPK1AOC3 | |
| SCHEMBL9824208 | 0.79 | RIPK1 (0.64) | TSHRRECQLSLC2A1RIPK1AOC3 | |
| SCHEMBL11447801 | 0.77 | RIPK1 (0.46) | TSHRRECQLSLC2A1RIPK1AOC3 | |
| SCHEMBL25711795 | 0.75 | RIPK1 (0.59) | TSHRRECQLRIPK1AOC3ALDH1A1 | |
| SCHEMBL14540715 | 0.75 | RIPK1 (0.59) | TSHRRECQLSLC2A1RIPK1AOC3 | |
| SCHEMBL9841880 | 0.72 | TSHR (0.52) | TSHRRECQLSLC2A1RIPK1AOC3 | |
| SCHEMBL30798978 | 0.70 | TAAR1 (0.66) | TSHRRECQLRIPK1AOC3ALDH1A1 | |
| SCHEMBL8290710 | 0.70 | TAAR1 (0.66) | TSHRRECQLRIPK1AOC3ALDH1A1 | |
| SCHEMBL17278345 | 0.70 | RIPK1 (0.61) | TSHRRECQLRIPK1AOC3ALDH1A1 | |
| SCHEMBL29565507 | 0.70 | RIPK1 (0.65) | TSHRRECQLRIPK1AOC3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |