Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.42 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434588 | 0.75 | SLC2A1 (0.59) | TSHRRECQLSLC2A1RIPK1PTGES | |
| SCHEMBL9824208 | 0.73 | RIPK1 (0.64) | TSHRRECQLSLC2A1RIPK1PYCR1 | |
| SCHEMBL9209224 | 0.72 | TSHR (0.55) | TSHRRECQLSLC2A1RIPK1PTGES | |
| SCHEMBL9214534 | 0.72 | TSHR (0.55) | TSHRRECQLSLC2A1RIPK1PTGES | |
| SCHEMBL7453269 | 0.72 | CHRM2 (0.49) | TSHRSLC2A1RIPK1ALDH1A1GAA | |
| SCHEMBL25711795 | 0.70 | RIPK1 (0.59) | TSHRRECQLRIPK1PYCR1PNMT | |
| SCHEMBL4781067 | 0.70 | PNMT (0.59) | TSHRRECQLSLC2A1RIPK1MAOA | |
| SCHEMBL19208209 | 0.69 | TSHR (0.48) | TSHRRECQLSLC2A1RIPK1PTGES | |
| SCHEMBL4877499 | 0.69 | BCHE (0.42) | PTGES | |
| SCHEMBL9209218 | 0.69 | NPC1 (0.51) | TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |