Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218206 | 0.80 | NR3C1 (0.44) | — | |
| SCHEMBL9214645 | 0.79 | NR3C1 (0.45) | RAB9AKDM4EALDH1A1 | |
| SCHEMBL13869116 | 0.76 | BRD4 (0.39) | FABP4 | |
| SCHEMBL3527949 | 0.74 | FABP4 (0.52) | FABP4MCL1KDM4EALDH1A1 | |
| SCHEMBL6564672 | 0.71 | EPHX1 (0.57) | — | |
| SCHEMBL3525455 | 0.69 | KDM4E (0.55) | FABP4KDM4EALDH1A1 | |
| SCHEMBL2291802 | 0.68 | NPC1 (0.63) | NPC1RAB9ATAAR1KDM4EALDH1A1 | |
| SCHEMBL13719793 | 0.68 | TRPV1 (0.41) | FABP4 | |
| SCHEMBL2290484 | 0.68 | GPR52 (0.52) | NPC1RAB9ATAAR1KDM4EALDH1A1 | |
| SCHEMBL4625378 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538469-B1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5360822-A | FOR TREATING URINARY INCONTINENCE IN ANIMALS AND HUMANS | NIPPON SHINYAKU CO. LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0538469-A1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-28 | — | — | EP | disclosed |