Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218206 | 0.90 | NR3C1 (0.44) | NR3C1PGRNR3C2AR | |
| SCHEMBL9214656 | 0.79 | ADRB3 (0.47) | RAB9AKDM4EALDH1A1 | |
| SCHEMBL9219341 | 0.76 | NR3C1 (0.44) | NR3C1PGRNR3C2AR | |
| SCHEMBL13869116 | 0.75 | BRD4 (0.39) | — | |
| SCHEMBL9211896 | 0.74 | NR3C1 (0.51) | NR3C1RAB9ANR3C2AR | |
| SCHEMBL9689716 | 0.73 | NR3C2 (0.56) | NR3C1RAB9AKDM4EALDH1A1NR3C2 | |
| SCHEMBL3527949 | 0.73 | FABP4 (0.52) | KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9219585 | 0.73 | NR3C1 (0.50) | NR3C1RAB9ANR3C2AR | |
| SCHEMBL3525455 | 0.68 | KDM4E (0.55) | KDM4EALDH1A1 | |
| SCHEMBL11286397 | 0.68 | ACHE (0.50) | MEN1KMT2ARAB9ATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538469-B1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5360822-A | FOR TREATING URINARY INCONTINENCE IN ANIMALS AND HUMANS | NIPPON SHINYAKU CO. LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0538469-A1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-28 | — | — | EP | disclosed |