SCHEMBL9214730

SCHEMBL9214730

CCc1c(N)cccc1NC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.47
TSHR P16473 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HPGD P15428 2/20 0.46
HDAC1 Q13547 3/20 0.44
HDAC3 O15379 2/20 0.44
HDAC2 Q92769 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.42
HSD17B10 Q99714 2/20 0.42
MAOA P21397 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
POLB P06746 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10072797 0.87 MAPK1 (0.55) MAPK1TSHRALDH1A1HPGDSMN1; SMN2
SCHEMBL11679849 0.83 ALDH1A1 (0.43) MAPK1TSHRALDH1A1HPGDHDAC1
SCHEMBL3940043 0.82 MAPK1 (0.50) MAPK1TSHRALDH1A1HPGDSMN1; SMN2
SCHEMBL8547885 0.81 MAPK1 (0.49) MAPK1TSHRALDH1A1HPGDHDAC1
SCHEMBL22289678 0.80 SIRT2 (0.51) MAPK1TSHRALDH1A1HPGDSMN1; SMN2
SCHEMBL24603810 0.79 ALDH1A1 (0.48) MAPK1TSHRALDH1A1HPGDHDAC1
SCHEMBL9608995 0.79 PKM (0.57) MAPK1TSHRALDH1A1HPGDSMN1; SMN2
SCHEMBL3633430 0.79 ALDH1A1 (0.54) MAPK1TSHRALDH1A1HPGDHDAC1
SCHEMBL5649435 0.79 RXFP1 (0.42) ALDH1A1HPGDHDAC1HDAC3HDAC2
SCHEMBL5516360 0.78 ALDH1A1 (0.52) MAPK1TSHRALDH1A1HPGDHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995002848-A1 MULTIFUNCTIONAL AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-26 WO disclosed