Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672238 | 0.72 | TAAR1 (0.57) | MAOBKIF11TAAR1ALDH1A1TSHR | |
| SCHEMBL5146089 | 0.71 | PTGS2 (0.47) | PTGS2MAPTKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9371761 | 0.71 | TAAR1 (0.55) | MAOBKIF11TAAR1ALDH1A1TSHR | |
| SCHEMBL28914110 | 0.69 | NPC1 (0.50) | PTGS2MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL7797358 | 0.69 | PTPN1 (0.60) | PTGS2KDM4EKMT2AALDH1A1HTT | |
| SCHEMBL8038496 | 0.67 | PTGS2 (0.51) | PTGS2MAPTALDH1A1NPC1POLB | |
| SCHEMBL1181119 | 0.67 | PTGS2 (0.73) | PTGS2 | |
| Ammonia Solution, Strong SCHEMBL23908221 | 0.65 | PTGS2 (0.71) | PTGS2 | |
| SCHEMBL2779082 | 0.65 | PTGS2 (0.50) | PTGS2MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL11594206 | 0.65 | PRMT6 (0.49) | KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492178-B1 | Naphthoic acid derivative | FUJIREBIO KK (JP) | 1995-10-04 | — | — | EP | disclosed |
| US-5324728-A | Lipoxygenase inhibiting antiallergens | FUJIREBIO INC. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0492178-A2 | Naphthoic acid derivative | FUJIREBIO INC. (JP) | 1992-07-01 | — | — | EP | disclosed |