Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829630 | 0.81 | ALOX5 (0.46) | CYP3A4CXCR2NPC1LMNAHTT | |
| SCHEMBL9829636 | 0.81 | ALOX5 (0.46) | CYP3A4CXCR2NPC1LMNAHTT | |
| SCHEMBL9214749 | 0.74 | EPHX2 (0.43) | EPHX2MEN1KMT2A | |
| SCHEMBL9214756 | 0.74 | EPHX2 (0.43) | EPHX2MEN1KMT2A | |
| SCHEMBL8466544 | 0.73 | MEN1 (0.71) | CYP3A4EPHX2MEN1KMT2ALMNA | |
| SCHEMBL9829583 | 0.73 | CXCR2 (0.42) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9829581 | 0.73 | CXCR2 (0.42) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8468027 | 0.72 | MEN1 (0.69) | CYP3A4EPHX2MEN1KMT2ALMNA | |
| SCHEMBL28827908 | 0.72 | EPHX2 (0.44) | HDAC6EPHX2MEN1KMT2ACETP | |
| SCHEMBL18112741 | 0.71 | KMT2A (0.43) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499521-B1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0499521-A1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-08-19 | — | — | EP | disclosed |