Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829630 | 1.00 | ALOX5 (0.46) | ALOX5ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL4370388 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDHTTSMN1; SMN2 | |
| SCHEMBL9829581 | 0.81 | CXCR2 (0.42) | ALOX5ALDH1A1MAPTCYP2C19RECQL | |
| SCHEMBL9829583 | 0.81 | CXCR2 (0.42) | ALOX5ALDH1A1MAPTCYP2C19RECQL | |
| SCHEMBL23748784 | 0.81 | ALDH1A1 (0.49) | ALOX5ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL9214760 | 0.81 | HDAC6 (0.41) | CXCR2L3MBTL1CYP3A4RAB9AHTT | |
| SCHEMBL18112741 | 0.80 | KMT2A (0.43) | MAPTCYP2C19RECQLCXCR2L3MBTL1 | |
| SCHEMBL12286073 | 0.80 | ALOX5 (0.51) | ALOX5ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL9828915 | 0.79 | KDM4E (0.51) | ALDH1A1MAPTHPGDRECQLCXCR2 | |
| SCHEMBL9828908 | 0.79 | KDM4E (0.51) | ALDH1A1MAPTHPGDRECQLCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |