Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739700 | 0.95 | GRM5 (0.41) | SLC6A4HTR1AHRH3GRM5ACHE | |
| SCHEMBL9213420 | 0.93 | HRH3 (0.46) | SLC6A4HTR1AHRH3GRM5SIGMAR1 | |
| SCHEMBL9207074 | 0.89 | GRM5 (0.42) | HRH3GRM5SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9213427 | 0.89 | GRM5 (0.42) | HRH3GRM5SIGMAR1 | |
| SCHEMBL9215099 | 0.88 | ADRA1B (0.46) | SLC6A4HTR1AHRH3ACHESIGMAR1 | |
| SCHEMBL9215558 | 0.88 | GRM5 (0.41) | HRH3GRM5SIGMAR1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL9209695 | 0.88 | ADRA1B (0.46) | SLC6A4HTR1AACHE | |
| SCHEMBL9215483 | 0.84 | HTR1A (0.44) | SLC6A4HTR1A | |
| Bromide SCHEMBL9206535 | 0.84 | KDM2B (0.39) | SLC6A4HTR1AACHE | |
| Hydrochloric Acid SCHEMBL9213668 | 0.83 | ABCB1 (0.46) | SLC6A4HTR1AGRM5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |