Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718279 | 0.79 | HDAC1 (0.62) | POLBHDAC1HDAC6ALDH1A1GAA | |
| SCHEMBL9220140 | 0.77 | ALDH1A1 (0.39) | ALDH1A1GAAPLOD2LMNAHIF1A | |
| SCHEMBL283481 | 0.77 | HDAC1 (0.60) | POLBHDAC1HDAC6ALDH1A1GAA | |
| SCHEMBL4211209 | 0.77 | KMT2A (0.43) | POLBHDAC1HDAC6ALDH1A1GAA | |
| SCHEMBL4921939 | 0.76 | F7 (0.52) | POLBHDAC1HDAC6ALDH1A1GAA | |
| SCHEMBL14595304 | 0.76 | ALDH1A1 (0.52) | HDAC1HDAC6ALDH1A1GAAAPP | |
| SCHEMBL15588644 | 0.73 | F7 (0.53) | POLBHDAC1HDAC6ALDH1A1GAA | |
| SCHEMBL16791193 | 0.73 | ALDH1A1 (0.49) | HDAC1HDAC6ALDH1A1GAAAPP | |
| SCHEMBL4657670 | 0.72 | LMNA (0.54) | ALDH1A1GAALMNAHIF1AMAPT | |
| SCHEMBL30285253 | 0.72 | POLB (0.59) | POLBHDAC1HDAC6ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5140109-A | — | — | None | — | — | JP | disclosed |
| EP-0388528-B1 | Carboximidamide derivatives | KIRIN BREWERY (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |
| JP-H05140109-A | PRODUCTION OF N-CYANO-N'-(2-NITROXYETHYL)-3-PYRIDINECARBOXYIMIDAMIDE | KIRIN BREWERY CO LTD | 1993-06-08 | — | — | JP | disclosed |
| US-5166347-A | Hypotensive agents, cardiovascular disorders, antiischemic agents and anticoagulants | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0388528-A2 | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1990-09-26 | — | — | EP | disclosed |