SCHEMBL4211209

SCHEMBL4211209

N#CNC(=N)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
C1S P09871 1/20 0.43
PRSS3 P35030 1/20 0.43
RECQL P46063 1/20 0.43
F2 P00734 1/20 0.41
F10 P00742 1/20 0.41
F12 P00748 1/20 0.41
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
PKM P14618 1/20 0.41
BLM P54132 1/20 0.39
ALDH1A1 P00352 3/20 0.38
POLB P06746 1/20 0.38
S1PR3 Q99500 2/20 0.37
S1PR4 O95977 1/20 0.37
GAA P10253 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390454 0.88 WDR5 (0.48) KMT2APRSS1PRSS2PRSS3ALDH1A1
SCHEMBL9220140 0.78 ALDH1A1 (0.39) KMT2ABLMALDH1A1GAACYP1A2
SCHEMBL13140955 0.77 C1S (0.52) KMT2AC1SALDH1A1MEN1HPGD
SCHEMBL15660513 0.77 KMT2A (0.47) KMT2APKMALDH1A1POLBCYP1A2
SCHEMBL9215228 0.77 POLB (0.50) KMT2AF7F3ALDH1A1POLB
SCHEMBL14625656 0.73 SMN1; SMN2 (0.31) PRSS1PRSS2PRSS3SMN1; SMN2
SCHEMBL262369 0.73 ALOX15 (0.54) KMT2AALDH1A1POLBGAAALOX15
SCHEMBL11400756 0.72 ALDH1A1 (0.46) KMT2APRSS1PRSS2C1SPRSS3
SCHEMBL3198029 0.72 F2 (0.50) KMT2APRSS1PRSS2C1SPRSS3
SCHEMBL5067711 0.72 F2 (0.50) KMT2APRSS1PRSS2C1SPRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151517-A1 THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN WAVEBREAK THERAPEUTICS LIMITED (US) 2025-07-17 WO disclosed
US-20220140257-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2022-05-05 US disclosed
CN-104768932-B The heteroaryl inhibitors of PDE4 泰特拉探索合伙有限责任公司 2018-08-07 CN disclosed
CN-107533293-A Positive photosensitive resin composition for display device and display device comprising same 株式会社东进世美肯 2018-01-02 CN disclosed
US-7485723-B2 Process for making trisaryl triazine UV absorbers using Lewis acids and reaction promoters CYTEC TECHNOLOGY CORP. (US) 2009-02-03 US disclosed
US-20070015920-A1 Process for Making Trisaryl Triazine UV Absorbers Using Lewis Acids and Reaction Promoters GUPTA RAM B 2007-01-18 US disclosed
EP-1131305-B1 PROCESS FOR PREPARING TRIAZINES USING A COMBINATION OF LEWIS ACIDS WITH REACTION PROMOTERS CYTEC TECH CORP (US) 2006-11-02 EP disclosed
US-20050165231-A1 Process for making triazine UV absorbers using Lewis acids and reaction promoters GUPTA RAM B (US) 2005-07-28 US disclosed
US-6900314-B2 Process for making triazine UV absorbers using lewis acids and reaction promoters CYTEC TECHNOLOGY CORP. (US) 2005-05-31 US disclosed
US-20040204585-A1 Process for making triazine UV absorbers using lewis acids and reaction promoters GUPTA RAM B (US) 2004-10-14 US disclosed
US-6730785-B2 COMPRISING LEWIS ACID AND REACTION PROMOTER IN AN AMOUNT SUFFICIENT TO SYNTHESIZE TRIAZINE COMPOUNDS AT LOWER REACTION TEMPERATURES, GREATER YIELDS, OR HIGHER SELECTIVITIES COMPARED TO LEWIS ACID ALONE CYTEC TECHNOLOGY CORP. 2004-05-04 US disclosed
US-6710177-B2 REACTING A CYANURIC HALIDE WITH BENZENE COMPOUND CYTEC TECHNOLOGY CORP. 2004-03-23 US disclosed
US-6486316-B1 Process for making triazine UV absorbers using Lewis acids and reaction promoters CYTEC TECHNOLOGY CORP. 2002-11-26 US disclosed
US-20020013463-A1 Process for making triazine UV absorbers using Lewis acids and reaction promoters CYTEC INDUSTRIES CORP. 2002-01-31 US disclosed
EP-1131305-A1 PROCESS FOR PREPARING TRIAZINES USING A COMBINATION OF LEWIS ACIDS WITH REACTION PROMOTERS CYTEC TECHNOLOGY CORP. (US) 2001-09-12 EP disclosed
US-20010020094-A1 Process for making triazine UV absorbers using lewis acids and reaction promoters CYTEC TECHNOLOGIES CORP. 2001-09-06 US disclosed
WO-2000029392-A1 PROCESS FOR PREPARING TRIAZINES USING A COMBINATION OF LEWIS ACIDS AND REACTION PROMOTERS CYTEC TECHNOLOGY CORP. (US) 2000-05-25 WO disclosed
EP-0051067-A1 TRIAZINE SYNTHESIS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1982-05-12 EP disclosed
WO-1981003020-A1 TRIAZINE SYNTHESIS COMMW SCIENT IND RES ORG (AU) 1981-10-29 WO disclosed
US-4246272-A TREATMENT OF GASTIC OR DUODENUM ULCERS ARON S.A. (FR) 1981-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220140257-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OCIAD2, OCIAD1, OXER1 KMT2A 3674/4885PRSS1 4583/4885PRSS2 4432/4885
US-20040204585-A1 Process for making triazine UV absorbers using lewis acids and reaction promoters TYR, TDO2, CYP4Z1 KMT2A 461/4885PRSS1 2470/4885PRSS2 1536/4885
US-20020013463-A1 Process for making triazine UV absorbers using Lewis acids and reaction promoters TYR, TDO2, CYP4Z1 KMT2A 461/4885PRSS1 2470/4885PRSS2 1536/4885
US-20050165231-A1 Process for making triazine UV absorbers using Lewis acids and reaction promoters TYR, TDO2, CYP4Z1 KMT2A 461/4885PRSS1 2470/4885PRSS2 1536/4885
US-20070015920-A1 Process for Making Trisaryl Triazine UV Absorbers Using Lewis Acids and Reaction Promoters TYR, TDO2, CYP4Z1 KMT2A 491/4885PRSS1 2283/4885PRSS2 1348/4885
US-20010020094-A1 Process for making triazine UV absorbers using lewis acids and reaction promoters TYR, TDO2, CYP4Z1 KMT2A 461/4885PRSS1 2470/4885PRSS2 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.