Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.53 |
| ▸ | CTSB | P07858 | 5/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 5/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326055 | 0.94 | CTSK (0.51) | CTSKCTSBPSMB5RENCASP3 | |
| SCHEMBL31326056 | 0.94 | CTSK (0.51) | CTSKCTSBPSMB5RENCASP3 | |
| SCHEMBL7303642 | 0.94 | CTSK (0.56) | CTSKCTSBPSMB5RENCASP3 | |
| SCHEMBL7886933 | 0.88 | CTSK (0.53) | CTSKCTSBPSMB5RENCASP3 | |
| SCHEMBL18342569 | 0.88 | CTSK (0.55) | CTSKCTSBPSMB5RENSYK | |
| SCHEMBL20263594 | 0.88 | CTSK (0.55) | CTSKCTSBPSMB5RENSYK | |
| SCHEMBL30645045 | 0.86 | REN (0.55) | CTSKCTSBREN | |
| SCHEMBL7304605 | 0.85 | HTT (0.46) | CTSKCTSBPSMB5CASP3CASP1 | |
| SCHEMBL19944560 | 0.85 | ECE1 (0.50) | CTSKCTSBPSMB5RENCASP3 | |
| SCHEMBL17261861 | 0.84 | CTSK (0.52) | CTSKCTSBPSMB5RENCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |