Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.56 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208530 | 0.94 | BCHE (0.50) | BCHEACHEFAAHABCC4CACNA1F | |
| SCHEMBL9207082 | 0.92 | BCHE (0.48) | BCHEACHEFAAHABCC4CACNA1F | |
| SCHEMBL9216358 | 0.85 | PDE4B (0.49) | ACHEDRD4MAOBPDE4D | |
| Hydrochloric Acid SCHEMBL9211501 | 0.83 | ALDH1A1 (0.49) | ACHEMAOBKDM4E | |
| Hydrochloric Acid SCHEMBL9215814 | 0.83 | PDE4B (0.48) | BCHEACHEDRD4PDE4DKDM4E | |
| SCHEMBL31134765 | 0.83 | GRM5 (0.60) | BCHEACHEFAAHABCC4CACNA1F | |
| SCHEMBL9215099 | 0.82 | ADRA1B (0.46) | BCHEACHEFAAHABCC4CACNA1F | |
| SCHEMBL9206607 | 0.82 | ADRA1B (0.49) | ABCB1CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL9209695 | 0.82 | ADRA1B (0.46) | BCHEACHEABCB1KDM4E | |
| Hydrochloric Acid SCHEMBL9213924 | 0.82 | ADRA1B (0.49) | ABCB1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |
| EP-0292840-A2 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |