SCHEMBL921559

SCHEMBL921559

CCc1ccc(Oc2cccc(CC)c2O)cc1O

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
AR P10275 1/20 0.42
CALM1 P0DP23 1/20 0.40
IDO1 P14902 1/20 0.40
ALOX5 P09917 1/20 0.39
PTGS2 P35354 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
POLB P06746 2/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
EGLN2 Q96KS0 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
CAMK2A Q9UQM7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921117 0.88 GABRA1 (0.48) GABRA1GABRB2ARCALM1ALOX5
SCHEMBL12806589 0.84 AR (0.43) ARALOX15ALOX12POLBHTR2A
SCHEMBL921465 0.81 POLB (0.47) POLB
SCHEMBL921504 0.81 GABRA1 (0.67) GABRA1GABRB2CALM1IDO1ALOX5
SCHEMBL12806837 0.79 CYP3A4 (0.51) GABRA1GABRB2POLBCAMK2A
SCHEMBL12806640 0.77 LTA4H (0.53) ALOX15ALOX12POLBCAMK2A
SCHEMBL12806942 0.76 TRPA1 (0.45) POLB
SCHEMBL12806918 0.76 LTA4H (0.55) POLB
SCHEMBL12806563 0.75 MAOB (0.44)
SCHEMBL921158 0.75 ESR1 (0.46) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
EP-1770447-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY MITSUBISHI CHEM CORP (JP) 2011-03-16 EP disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
EP-2154575-A2 Electrophotographic photoreceptor Mitsubishi Chemical Corporation (JP) 2010-02-17 EP disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed