Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468444 | 0.85 | RAB9A (0.42) | TRPA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL16774819 | 0.83 | ALDH1A1 (0.39) | RAB9ANPC1ALDH1A1POLBMAPT | |
| SCHEMBL9216970 | 0.81 | ALDH1A1 (0.41) | RAB9ANPC1ALDH1A1KMT2APOLB | |
| SCHEMBL160524 | 0.79 | MAOB (0.41) | RAB9ANPC1ALDH1A1KMT2APOLB | |
| SCHEMBL160525 | 0.79 | MAOB (0.41) | RAB9ANPC1ALDH1A1KMT2APOLB | |
| Phosphonic Acid SCHEMBL8609417 | 0.78 | RAB9A (0.39) | RAB9ANPC1ALDH1A1KMT2APOLB | |
| SCHEMBL4667275 | 0.78 | ALOX5 (0.42) | RAB9ANPC1ALDH1A1KMT2APOLB | |
| SCHEMBL11078186 | 0.78 | ALDH1A1 (0.36) | RAB9ANPC1ALDH1A1KMT2APOLB | |
| SCHEMBL23870570 | 0.77 | MAPT (0.39) | RAB9ANPC1ALDH1A1KMT2APOLB | |
| SCHEMBL7994546 | 0.77 | ALDH1A1 (0.37) | RAB9ANPC1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635018-A1 | 4-(1H-2-METHYLIMIDAZO 4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993016075-A1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |