Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160524 | 1.00 | MAOB (0.41) | MAOBRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL16774819 | 0.84 | ALDH1A1 (0.39) | MAOBRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL1993963 | 0.82 | ALDH1A1 (0.40) | MAOBRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL28468444 | 0.82 | RAB9A (0.42) | MAOBRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL27980365 | 0.81 | ALDH1A1 (0.37) | MAOBRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL3933026 | 0.81 | MAOB (0.45) | MAOBRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL27946214 | 0.81 | MAOB (0.45) | MAOBRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL105226 | 0.80 | — | — | |
| SCHEMBL28427145 | 0.80 | MAOB (0.39) | MAOBRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL19185911 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027101-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | Symrise GmbH & Co. KG (DE) | 2009-02-25 | — | — | EP | claimed |
| WO-2007131834-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2007-11-22 | — | — | WO | claimed |
| US-10851109-B2 | Compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease | MITOKININ LLC (US) | 2020-12-01 | — | — | US | disclosed |
| EP-2612376-B1 | SEMICONDUCTING COMPOUNDS AND RELATED COMPOSITIONS AND DEVICES | FLEXTERRA INC (US) | 2018-11-21 | — | — | EP | disclosed |
| EP-2704569-A1 | CARBONYL CONTAINING COMPOUNDS FOR CONTROLLING AND REPELLING CIMICIDAE POPULATIONS | Semiosbio Technologies Inc. (CA) | 2014-03-12 | — | — | EP | disclosed |
| US-8598575-B2 | Semiconducting compounds and related compositions and devices | POLYERA CORPORATION (US) | 2013-12-03 | — | — | US | disclosed |
| EP-2612376-A2 | SEMICONDUCTING COMPOUNDS AND RELATED COMPOSITIONS AND DEVICES | Polyera Corporation (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130168659-A1 | Semiconducting Compounds and Related Compositions and Devices | POLYERA CORPORATION (US) | 2013-07-04 | — | — | US | disclosed |
| WO-2012129702-A1 | CARBONYL CONTAINING COMPOUNDS FOR CONTROLLING AND REPELLING CIMICIDAE POPULATIONS | SEMIOSBIO TECHNOLOGIES INC. (CA) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012030662-A2 | SEMICONDUCTING COMPOUNDS AND RELATED COMPOSITIONS AND DEVICES | POLYERA CORPORATION (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20100022522-A1 | HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS | Incyte Corporationn, a Delaware corporation | 2010-01-28 | — | — | US | disclosed |
| EP-2027101-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | Symrise GmbH & Co. KG (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007131834-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2007-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130168659-A1 | Semiconducting Compounds and Related Compositions and Devices | NES, TST, SLC19A2 | MAOB 999/4885RAB9A 3260/4885NPC1 2814/4885 |
| US-10851109-B2 | Compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease | NLN, NME4, COQ8A | MAOB 251/4885RAB9A 927/4885NPC1 499/4885 |
| US-20100022522-A1 | HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS | JAK3, JAK1, JAK2 | MAOB 2038/4885RAB9A 2893/4885NPC1 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.