Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213879 | 0.94 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2AMAPTTP53 | |
| SCHEMBL9218677 | 0.93 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2AMAPTTP53 | |
| SCHEMBL9215732 | 0.93 | EGFR (0.38) | L3MBTL1MEN1KMT2AMAPTTP53 | |
| SCHEMBL5500482 | 0.92 | MEN1 (0.44) | L3MBTL1MEN1KMT2AMAPTTP53 | |
| SCHEMBL9217824 | 0.91 | L3MBTL1 (0.37) | L3MBTL1MEN1KMT2AMAPTTP53 | |
| SCHEMBL9218562 | 0.89 | MAPT (0.41) | L3MBTL1KMT2AMAPTTP53THRB | |
| SCHEMBL9221161 | 0.89 | L3MBTL1 (0.38) | NPC1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL9219657 | 0.89 | L3MBTL1 (0.36) | L3MBTL1MEN1KMT2AMAPTTP53 | |
| SCHEMBL9220046 | 0.88 | L3MBTL1 (0.36) | L3MBTL1MEN1KMT2AMAPTTP53 | |
| SCHEMBL9683150 | 0.87 | HTT (0.47) | L3MBTL1MEN1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |