Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213879 | 0.94 | L3MBTL1 (0.39) | MAPTPOLBPTPN1KMT2ACSNK2A2 | |
| SCHEMBL9218677 | 0.94 | L3MBTL1 (0.39) | MAPTPTPN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL9215732 | 0.93 | EGFR (0.38) | MAPTPTPN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL9217824 | 0.91 | L3MBTL1 (0.37) | MAPTMAOBPTPN1KMT2ACSNK2A2 | |
| SCHEMBL5500482 | 0.90 | MEN1 (0.44) | MAPTPTPN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL9681518 | 0.89 | NPC1 (0.39) | MAPTPTPN1KMT2AKDRCSNK2A2 | |
| SCHEMBL9219657 | 0.89 | L3MBTL1 (0.36) | MAPTPTPN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL9221161 | 0.87 | L3MBTL1 (0.38) | MAPTPTPN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL9220046 | 0.87 | L3MBTL1 (0.36) | MAPTMAOBPTPN1KMT2ACSNK2A2 | |
| SCHEMBL9213248 | 0.85 | KMT2A (0.40) | PTPN1KMT2AANO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |