Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 16/20 | 0.43 |
| ▸ | CDK2 | P24941 | 16/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229414 | 0.74 | CCNA2 (0.49) | CCNA2CDK2CCNA1 | |
| SCHEMBL25001210 | 0.69 | NPC1 (0.51) | CDK2DRD4 | |
| SCHEMBL21746971 | 0.66 | KDM4E (0.36) | — | |
| SCHEMBL21733674 | 0.63 | CCNA2 (0.35) | CCNA2CDK2CCNA1GRM4 | |
| SCHEMBL13981264 | 0.62 | — | — | |
| SCHEMBL9219954 | 0.62 | DRD4 (0.55) | DRD2DRD4MAPK10RIPK1 | |
| SCHEMBL9212932 | 0.62 | PIM1 (0.55) | CCNA2CDK2CCNA1DRD2DRD4 | |
| SCHEMBL6791745 | 0.62 | CCNA2 (0.64) | CCNA2CDK2CCNA1MAPK10RIPK1 | |
| SCHEMBL6333956 | 0.61 | CCNA2 (0.41) | CCNA2CDK2CCNA1GRM4 | |
| Hydrochloric Acid SCHEMBL6792455 | 0.60 | CCNA2 (0.74) | CCNA2CDK2CCNA1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276833-B1 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMA (US) | 1995-02-15 | — | — | EP | claimed |
| EP-0276833-A2 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-03 | — | — | EP | claimed |
| EP-0276833-B1 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMA (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0276833-A2 | Dipyrazoles useful as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4734430-A | Dipyrazoles and their use as bronchodilators | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-29 | — | — | US | disclosed |