SCHEMBL92163

SCHEMBL92163

Cc1ccc(/N=N/c2c(O)c(C(=O)Nc3ccccc3C)cc3ccccc23)c(S(=O)(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
CYP1A2 P05177 2/20 0.55
HIF1A Q16665 2/20 0.47
MPL P40238 4/20 0.47
PHLPP2 Q6ZVD8 1/20 0.45
F12 P00748 1/20 0.43
NQO2 P16083 1/20 0.43
THRB P10828 2/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CTRC Q99895 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
POLB P06746 2/20 0.41
GAA P10253 1/20 0.41
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17804076 0.89 THRB (0.54) ALDH1A1CYP1A2HIF1AF12NQO2
SCHEMBL30802166 0.89 ALDH1A1 (0.53) ALDH1A1CYP1A2HIF1AMPLPHLPP2
SCHEMBL17804092 0.87 LMNA (0.48) ALDH1A1CYP1A2F12NQO2THRB
SCHEMBL9289879 0.87 MRGPRX1 (0.51) ALDH1A1CYP1A2MPLLMNARAB9A
SCHEMBL92070 0.87 ALDH1A1 (0.50) ALDH1A1CYP1A2HIF1AMPLPHLPP2
SCHEMBL29362512 0.84 ALDH1A1 (0.72) ALDH1A1CYP1A2HIF1AMPLPHLPP2
SCHEMBL1161501 0.84 ALDH1A1 (0.72) ALDH1A1CYP1A2HIF1AMPLPHLPP2
SCHEMBL92057 0.84 ALDH1A1 (0.72) ALDH1A1CYP1A2HIF1AMPLPHLPP2
SCHEMBL29932227 0.84 ALDH1A1 (0.72) ALDH1A1CYP1A2HIF1AMPLPHLPP2
SCHEMBL29836201 0.83 KCNMA1 (0.48) ALDH1A1CYP1A2F12NQO2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2146230-B1 Binary diketopyrrolopyrrole pigment compound for use in colour filters CLARIANT FINANCE BVI LTD (VG) 2012-09-12 EP disclosed
EP-2145926-B1 PR 254 pigment preparation for use in colour filters CLARIANT FINANCE BVI LTD (VG) 2012-05-30 EP disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
US-8128848-B2 Diketopyrrolopyrrole pigment composition for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-06 US disclosed
EP-2205682-B1 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE BVI LTD (VG) 2011-03-09 EP disclosed
US-7892344-B2 P.R. 254 pigment preparation for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2011-02-22 US disclosed
US-7892344-B2 P.R. 254 pigment preparation for use in color filters CLARIANT FINANCE (BVI) LIMITED (VG) 2011-02-22 US disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
US-20100219384-A1 Diketopyrrolopyrrole Pigment Composition For Use In Color Filters CLARIANT FINANCE (BVI) LIMITED (VG) 2010-09-02 US disclosed
EP-2145926-A2 PR 254 pigment preparation for use in colour filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-20 EP disclosed
EP-2146230-A2 Binary diketopyrrolopyrrole pigment compound for use in colour filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-20 EP disclosed
US-20100006009-A1 P.R. 254 Pigment Preparation for use in Color Filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-14 US disclosed
US-20100006009-A1 P.R. 254 Pigment Preparation for use in Color Filters CLARIANT INTERNATIONAL LTD. (CH) 2010-01-14 US disclosed
WO-2009049736-A2 DIKETOPYRROLOPYRROLE PIGMENT COMPOSITION FOR USE IN COLOR FILTERS CLARIANT FINANCE (BVI) LIMITED (VG) 2009-04-23 WO disclosed