SCHEMBL921639

SCHEMBL921639

CCc1cc(C(C)c2cccc(CC)c2O)ccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.47
GABRB2 P47870 3/20 0.47
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
BCHE P06276 1/20 0.40
TYR P14679 1/20 0.40
ACHE P22303 1/20 0.40
BACE1 P56817 1/20 0.37
SLC6A4 P31645 1/20 0.37
RNASEH1 O60930 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
HSD17B1 P14061 1/20 0.36
TSHR P16473 3/20 0.35
CYP1A2 P05177 2/20 0.35
HIF1A Q16665 2/20 0.35
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922335 0.88 GABRA1 (0.47) GABRA1GABRB2BCHETYRACHE
SCHEMBL920814 0.82 ESR1 (0.50) GABRA1GABRB2ESR1ESR2TYR
SCHEMBL920328 0.82 GABRA1 (0.64) GABRA1GABRB2TSHRCYP1A2HIF1A
SCHEMBL10833197 0.81 GABRA1 (0.53) GABRA1GABRB2TYRTSHRCYP1A2
SCHEMBL3289099 0.76 ESR1 (0.57) ESR1ESR2TYRBACE1HSP90AA1
SCHEMBL1758248 0.76 ESR1 (0.44) GABRA1GABRB2ESR1ESR2BCHE
SCHEMBL921780 0.76 ESR1 (0.44) GABRA1GABRB2ESR1ESR2BACE1
SCHEMBL4459158 0.75 GABRA1 (0.64) GABRA1GABRB2TSHRCYP1A2HIF1A
SCHEMBL5167176 0.75 RNASEH1 (0.55) ESR1ESR2TYRBACE1RNASEH1
SCHEMBL16790388 0.74 ESR1 (0.43) ESR1ESR2BACE1HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105068389-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEM CORP 2015-11-18 CN disclosed
CN-102163013-B Electrophotographic photoreceptor and image forming apparatus using the same MITSUBISHI CHEM CORP 2015-02-18 CN disclosed
CN-102169298-B Image forming apparatus with a plurality of image forming units MITSUBISHI CHEM CORP 2014-01-08 CN disclosed
CN-101334592-B Electrophotographic photoreceptor MITSUBISHI CHEM CORP 2013-11-06 CN disclosed
CN-102156394-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-09-25 CN disclosed
CN-102221793-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-07-31 CN disclosed
CN-102169297-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-07-31 CN disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
CN-102937780-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEMICAL CO LTD 2013-02-20 CN disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
CN-101681133-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEMICAL CO LTD 2010-03-24 CN disclosed
EP-2154575-A2 Electrophotographic photoreceptor Mitsubishi Chemical Corporation (JP) 2010-02-17 EP disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
CN-101365987-A Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP (JP) 2009-02-11 CN disclosed
CN-101334592-A Electrophotographic photoreceptor MITSUBISHI CHEM CORP (JP) 2008-12-31 CN disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
CN-1985218-A Electrophotographic photoreceptor MITSUBISHI CHEM CORP (JP) 2007-06-20 CN disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed