SCHEMBL921780

SCHEMBL921780

CCc1ccc(C(C)c2ccc(O)c(CC)c2)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.44
ESR2 Q92731 4/20 0.44
BACE1 P56817 1/20 0.42
HSP90AA1 P07900 2/20 0.40
HSP90AB1 P08238 2/20 0.40
HSD17B1 P14061 1/20 0.40
SHBG P04278 1/20 0.40
ALOX15 P16050 3/20 0.39
ALOX12 P18054 1/20 0.39
HSD17B10 Q99714 2/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
ADRB2 P07550 1/20 0.37
PTGS2 P35354 1/20 0.37
OPRK1 P41145 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920814 0.93 ESR1 (0.50) ESR1ESR2BACE1HSP90AA1HSP90AB1
SCHEMBL922053 0.93 ALOX15 (0.44) ESR1ESR2HSP90AA1HSP90AB1SHBG
SCHEMBL3289099 0.86 ESR1 (0.57) ESR1ESR2BACE1HSP90AA1HSP90AB1
SCHEMBL16790388 0.84 ESR1 (0.43) ESR1ESR2BACE1HSP90AA1HSP90AB1
SCHEMBL5167176 0.81 RNASEH1 (0.55) ESR1ESR2BACE1HSP90AA1HSP90AB1
SCHEMBL4109681 0.81 TRPA1 (0.55) HSP90AA1HSP90AB1SHBGALOX15ALOX12
SCHEMBL11436873 0.78 ALOX15 (0.39) ESR1ESR2ALOX15ALOX12HSD17B10
SCHEMBL16736815 0.78 GAA (0.58) SHBGALOX15ALOX12HSD17B10USP2
SCHEMBL682798 0.78 GAA (0.62) ESR1ESR2BACE1HSP90AA1HSP90AB1
SCHEMBL3287169 0.78 ALOX5 (0.47) ESR1ESR2BACE1ALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105068389-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEM CORP 2015-11-18 CN disclosed
CN-102163013-B Electrophotographic photoreceptor and image forming apparatus using the same MITSUBISHI CHEM CORP 2015-02-18 CN disclosed
CN-102169298-B Image forming apparatus with a plurality of image forming units MITSUBISHI CHEM CORP 2014-01-08 CN disclosed
CN-101334592-B Electrophotographic photoreceptor MITSUBISHI CHEM CORP 2013-11-06 CN disclosed
CN-102156394-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-09-25 CN disclosed
CN-102169297-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-07-31 CN disclosed
CN-102221793-B Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP 2013-07-31 CN disclosed
US-8481238-B2 Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-09 US disclosed
CN-102937780-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEMICAL CO LTD 2013-02-20 CN disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
CN-101681133-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEMICAL CO LTD 2010-03-24 CN disclosed
EP-2154575-A2 Electrophotographic photoreceptor Mitsubishi Chemical Corporation (JP) 2010-02-17 EP disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
CN-101365987-A Electrophotographic photoreceptor, and image forming apparatus and electrophotographic photoreceptor cartridge using the same MITSUBISHI CHEM CORP (JP) 2009-02-11 CN disclosed
CN-101334592-A Electrophotographic photoreceptor MITSUBISHI CHEM CORP (JP) 2008-12-31 CN disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
CN-1985218-A Electrophotographic photoreceptor MITSUBISHI CHEM CORP (JP) 2007-06-20 CN disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed