Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 7/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212799 | 0.87 | LMNA (0.48) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL9220169 | 0.83 | LMNA (0.43) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL6840468 | 0.82 | LMNA (0.41) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL6840465 | 0.82 | LMNA (0.41) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL9220387 | 0.81 | CNR2 (0.43) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL9756955 | 0.77 | LMNA (0.46) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL9756952 | 0.77 | LMNA (0.46) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL29448323 | 0.76 | PRNP (0.53) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL1398747 | 0.76 | PRNP (0.53) | LMNAMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL3599532 | 0.75 | LMNA (0.71) | LMNAMAPK1CNR2CNR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |