Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214359 | 0.88 | LMNA (0.46) | LMNAMAPK1CNR2TDP1CNR1 | |
| SCHEMBL9216484 | 0.83 | LMNA (0.46) | LMNAMAPK1CNR2TDP1CNR1 | |
| SCHEMBL9220387 | 0.79 | CNR2 (0.43) | LMNAMAPK1CNR2TDP1CNR1 | |
| SCHEMBL8323182 | 0.71 | TUBB4A (0.48) | LMNAMAPK1CNR2TDP1L3MBTL1 | |
| SCHEMBL9212799 | 0.71 | LMNA (0.48) | LMNAMAPK1CNR2TDP1CNR1 | |
| SCHEMBL9033569 | 0.70 | BCL2L1 (0.57) | CNR2CNR1L3MBTL1RAB9A | |
| SCHEMBL7142280 | 0.70 | TUBB4A (0.36) | LMNAMAPK1CNR2TDP1CNR1 | |
| SCHEMBL7142284 | 0.70 | TUBB4A (0.36) | LMNAMAPK1CNR2TDP1CNR1 | |
| SCHEMBL8972816 | 0.68 | AKR1C2 (0.58) | LMNAMAPK1TDP1KDM4EMAPT | |
| SCHEMBL9219336 | 0.68 | MAPK1 (0.44) | LMNAMAPK1CNR2TDP1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |