Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209319 | 1.00 | LMNA (0.35) | LMNANAMPTSMN1; SMN2TSHRHTT | |
| SCHEMBL9211128 | 0.91 | TBXAS1 (0.40) | LMNANAMPTSMN1; SMN2TSHRHTT | |
| SCHEMBL9211118 | 0.91 | TBXAS1 (0.40) | LMNANAMPTSMN1; SMN2TSHRHTT | |
| SCHEMBL9216178 | 0.90 | MAPK1 (0.39) | LMNANAMPTSMN1; SMN2TSHRHTT | |
| SCHEMBL9217641 | 0.90 | MAPK1 (0.39) | LMNANAMPTSMN1; SMN2TSHRHTT | |
| SCHEMBL9213166 | 0.89 | KDM4E (0.41) | LMNASMN1; SMN2TSHRHTTTBXAS1 | |
| SCHEMBL9220380 | 0.89 | KDM4E (0.41) | LMNASMN1; SMN2TSHRHTTTBXAS1 | |
| SCHEMBL9212010 | 0.88 | MAPK1 (0.42) | LMNANAMPTSMN1; SMN2TSHRHTT | |
| SCHEMBL9210080 | 0.87 | CCR1 (0.35) | LMNANAMPTPKMHSD11B1 | |
| SCHEMBL9215202 | 0.87 | CCR1 (0.35) | LMNANAMPTPKMHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |