Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220380 | 1.00 | KDM4E (0.41) | KDM4ETBXAS1ALDH1A1TBXA2RCNR1 | |
| SCHEMBL9212010 | 0.92 | MAPK1 (0.42) | TBXAS1ALDH1A1GAALMNATSHR | |
| SCHEMBL9217641 | 0.92 | MAPK1 (0.39) | TBXAS1ALDH1A1CNR1GAALMNA | |
| SCHEMBL9216178 | 0.92 | MAPK1 (0.39) | TBXAS1ALDH1A1CNR1GAALMNA | |
| SCHEMBL9211118 | 0.92 | TBXAS1 (0.40) | TBXAS1ALDH1A1TBXA2RGAAL3MBTL1 | |
| SCHEMBL9211128 | 0.92 | TBXAS1 (0.40) | TBXAS1ALDH1A1TBXA2RGAAL3MBTL1 | |
| SCHEMBL9212029 | 0.90 | ALDH1A1 (0.43) | KDM4ETBXAS1ALDH1A1TBXA2RLMNA | |
| SCHEMBL9216984 | 0.90 | ALDH1A1 (0.43) | KDM4ETBXAS1ALDH1A1TBXA2RLMNA | |
| SCHEMBL9216640 | 0.89 | LMNA (0.35) | TBXAS1ALDH1A1CNR1GAALMNA | |
| SCHEMBL9209319 | 0.89 | LMNA (0.35) | TBXAS1ALDH1A1CNR1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |
| US-5364853-A | Treatment of disorders associated with vascular, respiratory, gastrointestinal tract, urinary bladder or uterus smooth muscle contraction | RHONE-POULENC RORER LIMITED (GB) | 1994-11-15 | — | — | US | claimed |
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | disclosed |
| US-5364853-A | Treatment of disorders associated with vascular, respiratory, gastrointestinal tract, urinary bladder or uterus smooth muscle contraction | RHONE-POULENC RORER LIMITED (GB) | 1994-11-15 | — | — | US | disclosed |