Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217189 | 0.88 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8TP53 | |
| SCHEMBL9219603 | 0.87 | ACLY (0.33) | GHSRGAAACLYCPT1AFABP4 | |
| SCHEMBL9211589 | 0.86 | MAPT (0.37) | HTR6TP53GHSRKDM4EGAA | |
| SCHEMBL9217235 | 0.83 | NPSR1 (0.35) | ABCC9ABCC8KCNJ11KCNJ8TP53 | |
| SCHEMBL9217252 | 0.83 | HTT (0.35) | TP53GHSRKDM4EGAAMAPT | |
| SCHEMBL9222097 | 0.82 | NPSR1 (0.34) | ABCC9ABCC8KCNJ11KCNJ8TP53 | |
| SCHEMBL9218306 | 0.80 | ACLY (0.33) | GHSRGAAKMT2AACLYCPT1A | |
| SCHEMBL9218094 | 0.80 | MAPT (0.35) | ABCC9ABCC8KCNJ11KCNJ8TP53 | |
| SCHEMBL7471418 | 0.78 | AVPR1B (0.43) | IDH1MAPT | |
| SCHEMBL9220670 | 0.77 | ROCK2 (0.36) | ACLYCPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |