Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219603 | 0.93 | ACLY (0.33) | GHSRRAPGEF3GAAACLY | |
| SCHEMBL9218306 | 0.89 | ACLY (0.33) | GHSRRAPGEF3GAAACLY | |
| SCHEMBL9221306 | 0.83 | IDH1 (0.34) | GHSRMAPTGAAKDM4EACLY | |
| SCHEMBL9211589 | 0.82 | MAPT (0.37) | HTTALDH1A1LMNASMN1; SMN2GHSR | |
| SCHEMBL9217189 | 0.80 | ABCC9 (0.34) | HTTALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL9217235 | 0.78 | NPSR1 (0.35) | HTTALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL7471248 | 0.78 | AVPR1B (0.42) | HTTTSHRMAPTCYP3A4 | |
| SCHEMBL9212844 | 0.78 | THRB (0.33) | HTTALDH1A1ADCY8LMNATSHR | |
| SCHEMBL9222097 | 0.77 | NPSR1 (0.34) | HTTALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL9220670 | 0.76 | ROCK2 (0.36) | LMNATSHRACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | disclosed |