SCHEMBL921723

SCHEMBL921723

COc1cccc(Sc2ccc(CNC(=O)c3cccnc3N)cc2)c1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.59
LMNA P02545 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
ALDH1A1 P00352 3/20 0.58
HPGD P15428 3/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
MAPT P10636 2/20 0.54
KDM4E B2RXH2 1/20 0.52
USP2 O75604 1/20 0.52
ATM Q13315 1/20 0.50
EGLN1 Q9GZT9 1/20 0.48
KLKB1 P03952 1/20 0.46
KLK1 P06870 1/20 0.46
APEX1 P27695 1/20 0.46
ROCK1 Q13464 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL923664 0.91 ALDH1A1 (0.69) POLBLMNASMN1; SMN2ALDH1A1HPGD
SCHEMBL920896 0.87 POLB (0.58) POLBLMNASMN1; SMN2ALDH1A1HPGD
SCHEMBL923068 0.85 HPGD (0.72) POLBLMNAALDH1A1HPGDKMT2A
SCHEMBL921595 0.85 ATM (0.67) POLBLMNASMN1; SMN2ALDH1A1HPGD
SCHEMBL921271 0.85 HPGD (0.57) POLBLMNASMN1; SMN2ALDH1A1HPGD
SCHEMBL921981 0.84 HPGD (0.70) POLBLMNASMN1; SMN2ALDH1A1HPGD
SCHEMBL923305 0.83 HPGD (0.60) POLBLMNASMN1; SMN2ALDH1A1HPGD
SCHEMBL919890 0.82 MAPK8 (0.50) POLBLMNASMN1; SMN2ALDH1A1HPGD
SCHEMBL922705 0.82 ATM (0.63) POLBLMNAALDH1A1HPGDKMT2A
SCHEMBL920983 0.81 HPGD (0.67) POLBLMNAALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 POLB 4159/4885LMNA 4812/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.