Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431067 | 0.94 | RXFP1 (0.62) | RXFP1TP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9219757 | 0.86 | TP53 (0.63) | TP53ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9216793 | 0.84 | POLB (0.58) | TP53ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9218097 | 0.84 | ALDH1A1 (0.62) | TP53ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9219577 | 0.83 | ALDH1A1 (0.52) | TP53ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9430659 | 0.83 | POLB (0.60) | TP53ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9221106 | 0.83 | POLB (0.60) | TP53ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9217619 | 0.83 | RXFP1 (0.51) | RXFP1TP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9681460 | 0.82 | RAB9A (0.59) | TP53ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9212926 | 0.81 | L3MBTL1 (0.57) | TP53ALDH1A1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |